Synthesis of benzimidazole by mortar–pestle grinding method
WEBOct 22, 2021 · Aldehydes (1 mmol), o phenylenediamines (1 mmol) were taken in an agate mortar and mL of acetic acid was added and the solution was gently ground by a pestle. The reaction mixture turned to a pasty mass after 15 min of grinding. The reaction mixture was quenched with water (3 mL) and diluted with ethyl acetate (5 mL).